Generic Name: Vitamin B Complex + Zinc
Manufacturer/Distributor: Aristopharma Limited
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Indications
Vitamin B complex is recommended for preventative or therapeutic nutritional supplementation in physiologically demanding settings. Glossitis, stomatitis, cheilosis, and beriberi are some of the conditions that cause B-vitamin deficiency or impaired absorption or bioavailability. Vitamin B complex is recommended for preventative or therapeutic nutritional supplementation in physiologically demanding settings. Glossitis, stomatitis, cheilosis, and beriberi are some of the conditions that cause B-vitamin deficiency or impaired absorption or bioavailability.
Pharmacology
The vitamin B complex contains the most important elements of the vitamin B group in pure form and in therapeutically adjusted amounts. Members of the vitamin B group are components of enzyme systems that regulate various stages of carbohydrate, lipid, and protein metabolism, with each component serving a distinct biological function. B vitamin deficiency symptoms include glossitis, stomatitis, cheilosis, polyneuritis, beriberi, pellagra, and corneal vascularization.
Dosage & Administration
Interaction
Gliclazide's hypoglycemic effects may be exacerbated by aspirin, NSAIDs, phenylbutazone, clofibrate, sulfonamide, cimetidine, imidazole antifungal medications, and monoamine oxidase inhibitors. Gliclazide's hypoglycemic effect may be reduced by Rifampin, Barbiturates, Phenytoin, Thiazide diuretics, Diazoxide, Glucocorticoids, Estrogens, Sympathomimetic medications, and Alcohol.
Contraindications
The following conditions should not be treated with gliclazide: Diabetes of juvenile-onset (type 1) Diabetes in conjunction with Ketosis Diabetic patients undergoing surgery, recovering from a serious accident, or suffering from an infection Patients who are allergic to the sulfonylurea class of medications Breast-feeding mothers and pregnant women Inadequate liver function.
Side Effects
There may be hypoglycaemia in concurrent conditions such as hepatic and renal disease, malnutrition, alcohol intoxication. Sometimes headache, gastrointestinal upsets, nausea, dizziness, skin reactions including rash, pruritus, erythema may occur.
Pregnancy & Lactation
Gliclazide is contraindicated in pregnant women. It should not be used in breast feeding mother.
Precautions & Warnings
Gliclazide should be used carefully in patients with hepatic impairment. If there is definite hepatic disease then gliclazide should not be used. Gliclazide can be used safely in patients with renal insufficiency as it is extensively metabolized. Gliclazide has less sudden hypoglycaemic episode than other sulfonylurea group of drugs
Storage Conditions
Protect from light and moisture by storing in a cool, dry place below 30°C. Keep out of children's reach.
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